Our Pipeline

BPD is a chronic severe lung disease primarily affecting extremely premature infants (< 28 weeks gestational age)  who require prolonged oxygen therapy to support their breathing. Prolonged mechanical ventilation can lead to inflammation and scarring of the lungs, which disrupts their normal development and repair. 

In developed countries, despite improved perinatal care, 40% of extremely preterm babies develop BPD, the most common and severe consequence of preterm birth. It remains the most common morbidity of prematurity*.

(*) Shah PS, Sankaran K, Aziz K, Allen AC, Seshia M, Ohlsson A, et al. Outcomes of preterm infants <29 weeks gestation over ten years in Canada: a cause for concern? J Perinatol. (2012) (https://pubmed.ncbi.nlm.nih.gov/21593814/)

Inflammatory Bowel Disease (IBD) is a group of chronic conditions that are characterized by inflammation in the digestive system. This includes Crohn's disease (CD) and ulcerative colitis (UC), both of which have an unknown cause. These conditions' development results from a complex interplay between genetic, immunological, and environmental factors.

It is estimated that 10 million individuals worldwide live with IBD. In the United States, the CDC estimated in 2015 that 1.3% of adults, equivalent to 3 million people, were affected by this condition.*

*IBD Statistics 2022: Crohn's and Ulcerative Colitis, https://ampersandhealth.co.uk/